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Late Show host David Letterman said goodbye Wednesday night with his trademark self-deprecating sarcasm. He left as he had arrived: with a hilarious show made on his own terms.

The Great Recession hit the industrial Midwest especially hard in recent years. Now, though, local leaders in at least one small Illinois city believe the worst is finally behind them. But they need to diversify — and attract new residents.

Long story short: The right is very, very Christian, while the left is much less so.

In important Super Tuesday states with a high number of born-again voters, Ted Cruz is losing to Donald Trump, and Marco Rubio is eating into his support with evangelicals.

U.S. officials were slow to provide details about the agreements announced during Trump's trip abroad. Many of the deals were nonbinding — others had been in the works since Obama's administration.

The Federal Emergency Management Agency expects 450,000 people to seek help — including over 30,000 needing shelter. But as floodwaters rise, those aren't the only numbers defining the rescue efforts.

The stage appears to be set for a renewed debate about gun control. The NRA and other proponents of gun owners' rights have been silent in the aftermath of the Newtown shootings, but many will question the benefits of possible restrictions.

In Boston, scientists are predicting that climate change will lead to dramatic sea level rise, and more frequent flooding, around the city. Officials are studying the potential impact on roads and sewers and are asking waterfront developers to plan for increased flooding.

Drones are no longer the sole province of the U.S. military and intelligence agencies. They are starting to appear in U.S. skies. Police are employing them to fight crime. Enthusiasts are making their own at home. Rules governing their use are changing, and civil liberties groups are calling for privacy restrictions.

The famed neurologist talks to Fresh Air about how grief, trauma, brain injury, medications and neurological disorders can trigger hallucinations — and about his personal experimentation with hallucinogenic drugs in the 1960s.