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People with tree-trunk-like legs who can't lose weight through diet and exercise may have lipedema, a lymphatic disorder. It's not clear what causes it, and most doctors aren't familiar with it.

Gov. Chris Christie says 108 people were injured after a train approached Hoboken Terminal at high speed and crashed into the platform. The roof of the New Jersey station has partially collapsed.

After Hillary Clinton's defeat, the Democratic Party is doing some soul-searching. NPR's Scott Simon talks to long-time Democratic strategist Tad Devine about how the party moves forward.

There are tons of tips on how to cook that Thanksgiving dinner, many of them rooted in science. Alton Brown, the showman of food TV, runs through why we stuff the turkey after it's cooked, why gravy should be kept in a thermos, and why canned cranberries are the devil.

The Trump transition team pointed to one heavily criticized study, as well as an analysis that didn't count fraud, as evidence that "millions of people" voted illegally.

New York Times cultural critic Wesley Morris joins Ari Shapiro to discuss how three departed stars — David Bowie, Prince and George Michael — helped change the meaning of manliness in pop culture.

Many people who are grateful for Obamacare are also frustrated by it. Three voters weigh in about their hopes and fears for the Affordable Care Act under a Trump administration.

The U.S. Attorney has issued several charges against 26-year-old Esteban Santiago for carrying out the deadly shooting. Maximum penalty is possible death sentence.

As President-elect Donald Trump tweets about expanding nuclear security and the cost of combat aircraft, some wonder whether his hardball posts are just "Art of the Deal" tactics to help the Pentagon.

Compared to its neighbors, Panama's cuisine is mostly unknown, even to locals. A new generation of Panamanian chefs is forging a national food identity using indigenous ingredients and techniques.