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Screenwriter Will Reiser coped with his cancer diagnosis by thinking up ideas for cancer comedy movies with his best friend, actor Seth Rogen. Rogen and actor Joseph Gordon-Levitt now star in a film based on Reiser's life. Both Gordon-Levitt and Reiser join Fresh Air for a conversation about the film.

A voluntary approach to flu vaccination of health care workers has fallen short. To protect patients, vaccination should be mandatory, consumer and business groups said in Washington. They back a requirement for annual vaccination of all health workers with only limited exemptions.

The Obama administration reaffirmed its position that certain religious institutions have to provide health coverage that offers free contraception. U.S. Catholic bishops are vowing to fight this rule in Congress, in courts, and in churches. Host Michel Martin speaks with Laurie Goodstein of the New York Times.

Sturgeon have been swimming around for more than 200 million years, but their eggs are sought after for caviar. This week, the National Marine Fisheries Service placed the Atlantic sturgeon on its endangered species list. Guest host David Greene speaks with Dr. Ellen Pikitch, executive director of the Institute for Ocean Conservation Science at Stony Brook University.

Though most people will never attend a single Super Bowl, there are three men who have seen them all. Don Crisman and Larry Jacobson are part of a group that calls itself the "Never Missed a Super Bowl Club," and they have no plans to end the streak any time soon. Guest host David Greene catches up with them as they prepare for Sunday's game in Indianapolis.

Nineteen Americans face criminal charges in Egypt over their work for U.S. non-profit organizations. The charges are part of an escalating stand-off between Egyptian officials and the U.S. Washington sends some $1.5 billion in aid to Egypt, and U.S. lawmakers say that's in jeopardy now.

The Susan G. Komen for the Cure Foundation is fighting to keep controversy from undermining its fundraising efforts. Komen spends tens of millions of dollars for cancer research, education and screening. But that spending was criticized long before the current flap over its Planned Parenthood grants.

Jamie King's NFL dreams never took off, but he got a second chance when he was asked to coach the Fredericksburg Generals, a little-known team in Virginia. He talks with guest host Jacki Lyden about helping a group of misfits become champions, and how it changed his life in the process. King is profiled in this week's The Washington Post Magazine.

Thurston is the son of a pro-black, pan-African mother. He straddled the worlds between his troubled neighborhood in Washington, D.C., and the elite halls of Harvard University. He speaks with host Michel Martin about his new book How To Be Black.

About 1 in 5 nonsmoking kids in middle and high school reported sharing a car with a smoker. The researcher say the survey, which included responses from thousands of students, give an accurate snapshot of what's happening across the country.