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Indianapolis is honoring its own. After three decades, David Letterman is retiring from his late-night CBS show. Wednesday is his final broadcast.

LINCOLN, Neb. (AP) — A bill that would allow driver's licenses for immigrant youths brought to the country illegally as children has advanced to a final…

Governor Pete Ricketts says he’ll veto bills to repeal Nebraska’s death penalty and end mandatory minimum sentences for some crimes.The Nebraska…

Newly declassified materials include books, magazines and letters found during the 2011 raid on the al-Qaida leader's compound in Abbottabad, Pakistan.

Iowa Republican Sen. Chuck Grassley is asking the Obama administration pointed questions about what is being done to investigate alleged fraud, waste and abuse by Medicare Advantage plans.

Emails from informal adviser Blumenthal to Hillary Clinton on U.S. policy in Libya have been subpoenaed by a House committee. He's no stranger to controversy, but Clinton says he's just an old friend.

Aficionados of fine weed describe the effects as if they're talking about vintage wine. But how to know which medicinal or recreational strain to choose? This field guide cuts through the haze.

Stephanie Packer's debilitating illnesses leave her in a lot of pain. But she is opposed to a California bill that would legalize physician-assisted suicide.

David Letterman approached his final extra-long hour of late night TV on Wednesday with the same self-deprecation as the previous 6,000-plus, but leavened the snark with heaps of nostalgia and praise.

NPR's Robert Siegel speaks with David Ignatius, columnist for the Washington Post, about how the U.S. miscalculated the vulnerability of Ramadi, Iraq, to takeover by the self-declared Islamic State.